![C44H53FN7O8 Guanosina, 5′ -O- [bis(4-metoxifenil)fenilmetil]-2′ -desoxi-2′ – fluoro-N-(2-metil-1-oxopropil)-, 3′ – [2-zianoetil N,N-bis(1-metil etil)fosforamidita] (ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C44H53FN7O8 Guanosina, 5′ -O- [bis(4-metoxifenil)fenilmetil]-2′ -desoxi-2′ – fluoro-N-(2-metil-1-oxopropil)-, 3′ – [2-zianoetil N,N-bis(1-metil etil)fosforamidita] (ACI) Irudi nabarmena](https://www.csnvchem.com/uploads/C44H53FN7O8.png)
C44H53FN7O8 Guanosina, 5′ -O- [bis(4-metoxifenil)fenilmetil]-2′ -desoxi-2′ – fluoro-N-(2-metil-1-oxopropil)-, 3′ – [2-zianoetil N,N-bis(1-metil etil)fosforamidita] (ACI)
CAS Erregistro Zenbakia
144089-97-4
| Ezaugarri fisiko nagusiak | Balioa | Baldintza |
| Pisu molekularra | 857,91 | - |
| pKa (Aurreikusita) | 9,16 ± 0,20 | Tenperatura azidoena: 25 °C |
IRRIBARRE KANONIKOAK
N#CCCOP(OC1C(F)C(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C= NC=6C(=O)N=C(NC(=O)C(C)C)NC65)N(C(C)C)C(C)C
IRRIBARRE ISOMERIKOAK
C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@@H](O1)N2C3=C(N=C2)C(=O)N=C(NC(C(C)C)=O)N3)(C4=CC=C(OC)C =C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
InChI
InChI= 1S/C44H53FN7O8P/c1-27(2)40(53)49-43-48-39-37(41(54)50-43)47-26-51(39)42-36(45)38(60-61(58-24-162)(58-24-163)(42) 6)35(59-42)25-57-44(30-13-10-9-11-14-30,31-15-19-33(55-7)20-16- 31)32-17-21-34(56-8)22-18-32/h9-11,13-22,26-29,35-36,38,42H,12, 24-25H2,1-8H3,(H2,48,49,50,53,54)/t35-,36-,38-,42-,61?/m1/s1
InChI gakoa
KJFUMXZZVYMQEU-AOCJBPQJSA-N
Substantzia honen beste izen bat
Guanosina, 5′ -O- [bis(4-metoxifenil)fenilmetil]-2′-desoxi-2′-fluoro-N-(2-metil-1-oxopropil)-, 3′ - [2-zianoetil bis(1-metil etil)fosforamidita] (9CI)
Eskuragarri dauden propietateak
Biologikoa
Kimikoa
Lipinski
Egitura erlazionatua
| Jabetza | Balioa | Baldintza | Iturria |
| Biokontzentrazio faktorea | 298 | pH 1; Tenperatura: 25 °C | (1) ACD |
| Biokontzentrazio faktorea | 6350 | pH 2; Tenperatura: 25 °C | (1) ACD |
| Biokontzentrazio faktorea | 57800 | pH 3; Tenperatura: 25 °C | (1) ACD |
| Biokontzentrazio faktorea | 1,76 × 105 | pH 4; Tenperatura: 25 °C | (1) ACD |
| Biokontzentrazio faktorea | 2,21 × 105 | pH 5; Tenperatura: 25 °C | (1) ACD |
| Biokontzentrazio faktorea | 2,26 × 105 | pH 6; Tenperatura: 25 °C | (1) ACD |
| Biokontzentrazio faktorea | 2,24 × 105 | pH 7; Tenperatura: 25 °C | (1) ACD |
| Biokontzentrazio faktorea | 2,03 × 105 | pH 8; Tenperatura: 25 °C | (1) ACD |
| Biokontzentrazio faktorea | 1,04 × 105 | pH 9; Tenperatura: 25 °C | (1) ACD |
| Biokontzentrazio faktorea | 19300 | pH 10; Tenperatura: 25 °C | (1) ACD |
(1) Advanced Chemistry Development (ACD/Labs) Software V11.02 erabiliz kalkulatua (© 1994-2023 ACD/Labs)
| Jabetzaren balioaren baldintzaren iturria |
| Koc 312 pH 1; Tenperatura: 25 °C (1) ACD |
| Koc 6630 pH 2; Tenperatura: 25 °C (1) ACD |
| Koc 60400 pH 3; Tenperatura: 25 °C (1) ACD |
| Koc 1,84 x 105 pH 4; Tenperatura: 25 °C (1) ACD |
| Koc 2,31 x 105 pH 5; Tenperatura: 25 °C (1) ACD |
| Koc 2,37 x 105 pH 6; Tenperatura: 25 °C (1) ACD |
| Koc 2,35 x 105 pH 7; Tenperatura: 25 °C (1) ACD |
| Koc 2,12 x 105 pH 8; Tenperatura: 25 °C (1) ACD |
| Koc 1,08 x 105 pH 9; Tenperatura: 25 °C (1) ACD |
| Koc 20200 pH 10; Tenperatura: 25 °C (1) ACD |
| logD 4,47 pH 1; Tenperatura: 25 °C (1) ACD |
| logD 5,80 pH 2; Tenperatura: 25 °C (1) ACD |
| Jabetza | Balioa | Baldintza | Iturria |
| logD | 6,76 | pH 3; Tenperatura: 25 °C | (1) ACD |
| logD | 7.24 | pH 4; Tenperatura: 25 °C | (1) ACD |
| logD | 7.34 | pH 5; Tenperatura: 25 °C | (1) ACD |
| logD | 7.35 | pH 6; Tenperatura: 25 °C | (1) ACD |
| logD | 7.35 | pH 7; Tenperatura: 25 °C | (1) ACD |
| logD | 7.30 | pH 8; Tenperatura: 25 °C | (1) ACD |
| logD | 7.01 | pH 9; Tenperatura: 25 °C | (1) ACD |
| logD | 6.28 | pH 10; Tenperatura: 25 °C | (1) ACD |
| logP | 7,351 ± 0,713 | Tenperatura: 25 °C | (1) ACD |
| Masaren berezko disolbagarritasuna | 3,0 x 10-5 g/L | Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 0,022 g/L | pH 1; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 1,0 x 10-3 g/L | pH 2; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 1,2 x 10-4 g/L | pH 3; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 3,9 x 10-5 g/L | pH 4; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 3,1 x 10-5 g/L | pH 5; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 3,0 x 10-5 g/L | pH 6; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 3,0 x 10-5 g/L | pH 7; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 3,3 x 10-5 g/L | pH 8; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 6,5 x 10-5 g/L | pH 9; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 3,5 x 10-4 g/L | pH 10; Tenperatura: 25 °C | (1) ACD |
| Masa-disolbagarritasuna | 3,0 x 10-5 g/L | Tamperatu gabeko ura pH 7.00; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molar intrintsekoa | 3,5 x 10-8 mol/L | Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 2,6 x 10-5 mol/L | pH 1; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 1,2 x 10-6 mol/L | pH 2; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 1,4 x 10-7 mol/L | pH 3; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 4,5 x 10-8 mol/L | pH 4; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 3,6 x 10-8 mol/L | pH 5; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 3,5 x 10-8 mol/L | pH 6; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 3,5 x 10-8 mol/L | pH 7; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 3,9 x 10-8 mol/L | pH 8; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 7,6 x 10-8 mol/L | pH 9; Tenperatura: 25 °C | (1) ACD |
| Disolbagarritasun molarra | 4,1 x 10-7 mol/L | pH 10; Tenperatura: 25 °C | (1) ACD |
| Jabetza | Balioa | Baldintza | Iturria |
| Disolbagarritasun molarra | 3,5 x 10-8 mol/L | Tamperatu gabeko ura pH 7.00; Tenperatura: 25 °C | (1) ACD |
| Pisu molekularra | 857,91 | ||
| pKa | 9,16 ± 0,20 | Tenperatura azidoena: 25 °C | (1) ACD |
| pKa | 3,45 ± 0,70 | Oinarrizko tenperatura: 25 °C | (1) ACD |
(1) Advanced Chemistry Development (ACD/Labs) Software V11.02 erabiliz kalkulatua (© 1994-2023 ACD/Labs)
| Jabetza | Balioa | Baldintzaren iturria |
| Azalera polarra | 184 A2 | (1) ACD |
(1) Advanced Chemistry Development (ACD/Labs) Software V11.02 erabiliz kalkulatua (© 1994-2023 ACD/Labs)
| Jabetza | Balioa | Baldintza | Iturria |
| Libreki bira daitezkeen bonuak | 18 | (1) ACD | |
| H hartzailea | 15 | (1) ACD | |
| H Emaileak | 2 | (1) ACD | |
| H Emaile/Hartzaile Batura | 17 | (1) ACD | |
| logP | 7,351 ± 0,713 | Tenperatura: 25 °C | (1) ACD |
| Pisu molekularra | 857,91 |
(1) Advanced Chemistry Development (ACD/Labs) Software V11.02 erabiliz kalkulatua (© 1994-2023 ACD/Labs)
![C43H55N4O10P Uridina, 5′ -O- [bis(4-metoxifenil)fenilmetil]-2′ -O-(2-metoxietil)-5-metil-, 3′ – [2-zianoetil N,N-bis(1-metiletil)fosforamidita] (ACI)](https://www.csnvchem.com/uploads/C43H55N4O10P-Uridine-300x300.png)
![C47H51FN7O7P Adenosina, N-benzoil-5′ -O- [bis(4-metoxifenil)fenilmetil]-2′ – desoxi-2′ -fluoro-, 3′ – [2-zianoetil N,N-bis(1-metiletil)fosforo amidita] (ACI)](https://www.csnvchem.com/uploads/C47H51FN7O7P-Adenosine-300x300.png)
![C48H54N7O8P Adenosina, N-benzoil-5′ -O- [bis(4-metoxifenil)fenilmetil]-2′ – O-metil-, 3′ – [2-zianoetil N,N-bis(1-metiletil)fosforo amidita] (ACI)](https://www.csnvchem.com/uploads/C48H54N7O8P-300x300.png)
![C47H60N7O10P Guanosina, 5′ -O- [bis(4-metoxifenil)fenilmetil]-2′ -O-(2- metoxietil)-N-(2-metil-1-oxopropil)-, 3′ – [2-zianoetil N,N-bis (1-metiletil)fosforamidita] (ACI)](https://www.csnvchem.com/uploads/C47H60N7O10P-Guanosine-300x300.png)
![C50H58N7O9P Adenosina, N-benzoil-5′ -O- [bis(4-metoxifenil)fenilmetil]-2′ – O-(2-metoxietil)-, 3′ – [2-zianoetil N,N-bis(1-metiletil) fosforamidita] (ACI)](https://www.csnvchem.com/uploads/C50H58N7O9P-Adenosine-300x300.png)
![C40H49N4O9P Uridina, 5′ -O- [bis(4-metoxifenil)fenilmetil]-2′ -O-metil-, 3′ – [2-zianoetil N,N-bis(1-metiletil)fosforamidita] (ACI)](https://www.csnvchem.com/uploads/C40H49N4O9P-Uridine-300x300.png)