![C39H46FN4O8P Uridin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C39H46FN4O8P Uridin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI) Ausgewielt Bild](https://www.csnvchem.com/uploads/C39H46FN4O8P-Uridine.png)
C39H46FN4O8P Uridin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)
CAS-Registrierungsnummer
146954-75-8
| Schlësselphysikalesch Eegeschaften | Wäert | Zoustand |
| Molekulargewiicht | 748,78 | - |
| pKa (Virausbezunnen) | 9,39±0,10 | Säurege Temperatur: 25 °C |
Kanonesch Laachen
N#CCCOP(OC1C(F)C(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=CC(=O)NC5=O)N(C(C)C)C(C)C
Isomeresch Laachen
C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@@H](O1)N2C(=O)NC(=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C= C4)C5=CC=CC=C5
InChI
InChI= 1S/C39H46FN4O8P/c1-26(2)44(27(3)4)53(50-24-10-22-41)52-36-33(51-37(35(36)40)43-23-21-34(45)43)49-81(42)49(49) -8-7-9-12-28,29-13-17-31(47-5)18-14-29)30-15-19-32(48-6)20-16-3 0/h7-9,11-21,23,26-27,33,35-37H,10,24-25H2,1-6H3,(H,42,45,46)/t3 3-,35-,36-,37-,53?/m1/s1
InChI Schlëssel
HQHQPAYRJJMYQX-DJTPZYMWSA-N
1 Aneren Numm fir dës Substanz
Uridin, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluor-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidit] (9CI)
Verfügbar Immobilien
Biologesch
Chemesch
Lipinski
Strukturbezunnen
| Immobilie | Wäert | Zoustand | Quell |
| Biokonzentratiounsfaktor | 457 | pH 1; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 3690 | pH 2; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 27700 | pH 3; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 82900 | pH 4; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 1,04 x 105 | pH 5; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 1,06 x 105 | pH 6; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 1,06 x 105 | pH 7; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 1,02 x 105 | pH 8; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 76200 | pH 9; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 22000 | pH 10; Temperatur: 25 °C | (1) ACD |
(1) Berechent mat der Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Quell vum Zoustand vum Immobiliewäert |
| Koc 592 pH 1; Temperatur: 25 °C (1) ACD |
| Koc 4790 pH 2; Temperatur: 25 °C (1) ACD |
| Koc 36000 pH 3; Temperatur: 25 °C (1) ACD |
| Koc 1,07 x 105 pH 4; Temperatur: 25 °C (1) ACD |
| Koc 1,34 x 105 pH 5; Temperatur: 25 °C (1) ACD |
| Koc 1,38 x 105 pH 6; Temperatur: 25 °C (1) ACD |
| Koc 1,37 x 105 pH 7; Temperatur: 25 °C (1) ACD |
| Koc 1,33 x 105 pH 8; Temperatur: 25 °C (1) ACD |
| Koc 98800 pH 9; Temperatur: 25 °C (1) ACD |
| Koc 28600 pH 10; Temperatur: 25 °C (1) ACD |
| logD 4,55 pH 1; Temperatur: 25 °C (1) ACD |
| logD 5,46 pH 2; Temperatur: 25 °C (1) ACD |
| logD 6,33 pH 3; Temperatur: 25 °C (1) ACD |
| Immobilie | Wäert | Zoustand | Quell |
| logD | 6,81 | pH 4; Temperatur: 25 °C | (1) ACD |
| logD | 6,91 | pH 5; Temperatur: 25 °C | (1) ACD |
| logD | 6,92 | pH 6; Temperatur: 25 °C | (1) ACD |
| logD | 6,92 | pH 7; Temperatur: 25 °C | (1) ACD |
| logD | 6,90 | pH 8; Temperatur: 25 °C | (1) ACD |
| logD | 6,77 | pH 9; Temperatur: 25 °C | (1) ACD |
| logD | 6.23 | pH 10; Temperatur: 25 °C | (1) ACD |
| logP | 6,918±0,641 | Temperatur: 25 °C | (1) ACD |
| Masse intrinsesch Léislechkeet | 2,2 x 10-5 g/L | Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 5,1 x 10-3 g/L | pH 1; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 6,3 x 10-4 g/L | pH 2; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 8,2 x 10-5 g/L | pH 3; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,8 x 10-5 g/L | pH 4; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,2 x 10-5 g/L | pH 5; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,2 x 10-5 g/L | pH 6; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,2 x 10-5 g/L | pH 7; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,2 x 10-5 g/L | pH 8; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 3,0 x 10⁻⁶ g/L | pH 9; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 1,0 x 10⁻⁴ g/L | pH 10; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,2 x 10-5 g/L | Ongepuffert Waasser pH 7,00; Temperatur: 25 °C | (1) ACD |
| Molar intrinsesch Léislechkeet | 2,9 x 10-8 mol/L | Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 6,8 x 10⁻⁶ mol/L | pH 1; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 8,4 x 10⁻⁶ mol/L | pH 2; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 1,1 x 10⁻⁶ mol/L | pH 3; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 3,7 x 10-8 mol/L | pH 4; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 3,0 x 10⁻⁶ mol/L | pH 5; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 2,9 x 10-8 mol/L | pH 6; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 2,9 x 10-8 mol/L | pH 7; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 3,0 x 10⁻⁶ mol/L | pH 8; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 4,0 x 10-8 mol/L | pH 9; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 1,4 x 10⁻⁶ mol/L | pH 10; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 2,9 x 10-8 mol/L | Ongepuffert Waasser pH 7,00; Temperatur: 25 °C | (1) ACD |
| Immobilie | Wäert | Zoustand | Quell |
| Molekulargewiicht | 748,78 | ||
| pKa | 9,39±0,10 | Säurege Temperatur: 25 °C | (1) ACD |
| pKa | 3,45±0,70 | Basis Temperatur: 25 °C | (1) ACD |
(1) Berechent mat der Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Immobilie | Wäert | Zoustand | Quell |
| Fräi rotéierbar Bindungen | 17 | (1) ACD | |
| H-Akzeptoren | 12 | (1) ACD | |
| H Spender | 1 | (1) ACD | |
| H Donateur/Akzeptant Zomm | 13 | (1) ACD | |
| logP | 6,918±0,641 | Temperatur: 25 °C | (1) ACD |
| Molekulargewiicht | 748,78 |
(1) Berechent mat der Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Immobilie | Wäert | Quell vun der Konditioun |
| Polarfläche | 145 A2 | (1) ACD |
(1) Berechent mat der Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
![C41H49FN5O8P Cytidin, N-Acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluor-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C41H49FN5O8P-Cytidine-300x300.png)
![C40H49N4O9P Uridin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C40H49N4O9P-Uridine-300x300.png)
![C43H55N4O10P Uridin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C43H55N4O10P-Uridine-300x300.png)
![C47H51FN7O7P Adenosin, N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluor-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C47H51FN7O7P-Adenosine-300x300.png)
![C47H60N7O10P Guanosin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C47H60N7O10P-Guanosine-300x300.png)
![C53H66N7O8PSi CAS-Nr.: 104992-55-4 Adenosin, N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′–O-[(1,1-dimethylethyl)dimethylsilyl]-, 3′–[2-cyanoethyl N,N-bis(1-methylethyl)...](https://www.csnvchem.com/uploads/C53H66N7O8PSi-300x300.png)