C45H56N7O9P Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-methyl- N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N,N-bis (1-methylethyl) phosphoramidite] (ACI)

sehlahisoa

C45H56N7O9P Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-methyl- N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N,N-bis (1-methylethyl) phosphoramidite] (ACI)

Lintlha tsa Motheo:


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Tlhaloso ea Lintho

Nomoro ea Registry ea CAS

150780-67-9

H303

Lintho Tsa Bohlokoa Tsa 'Mele Boleng Boemo
Boima ba Molek'hule 869.94 -
pKa (E boletsoeng esale pele) 9.16±0.20 Mocheso o nang le Asiti ka ho Fetisisa: 25 °C

Mabitso a Mang le Litlhahiso

N#CCCOP(OC1C(OC(N2C= NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OC)COC(C=4C=CC=CC4)(C5=CC =C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

Isomeric SOSOA

C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@@ H](O1)N2C3=C(N=C2)C(=O)N=C(NC(C(C)C)=O)N3)(C4=CC=C(OC) C=C4)(C5 =CC=C(OC)C=C5)C6=CC=CC=C6

InChi

InChI= 1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9) 38(61-62(59-25-13-24-)

46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34( 55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27 -30,36,38-39,43H,13, 25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1

Senotlolo sa InChi

IRRDHRZUOZNWDJ-MLLDKZSOSA-N

1 Lebitso le Leng la Ntho ena

Guanosine, 5′-O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-methyl-N-(2-methyl-1-oxopropyl)-, 3′ - [2-cyanoethyl bis(1-methylethyl) phosphoramidite] (9CI)

Spectra ea Teko

Spectra e fumaneha
13 C NMR
Hetero NMR

Thepa e boletsoeng esale pele

Thepa e teng
Likokoana-hloko
Lik'hemik'hale
Lipinski
Sebopeho se Amanang

Likokoana-hloko

Thepa Boleng Boemo Mohloli
Bioconcentration Factor 183 pH 1;Mocheso: 25 °C (1) ACD
Bioconcentration Factor 3890 pH 2;Mocheso: 25 °C (1) ACD
Bioconcentration Factor 35500 pH 3;Mocheso: 25 °C (1) ACD
Bioconcentration Factor 1.08 x 105 pH 4;Mocheso: 25 °C (1) ACD
Bioconcentration Factor 1.36 x 105 pH 5;Mocheso: 25 °C (1) ACD
Bioconcentration Factor 1.39 x 105 pH 6;Mocheso: 25 °C (1) ACD
Bioconcentration Factor 1.38 x 105 pH 7;Mocheso: 25 °C (1) ACD
Bioconcentration Factor 1.24 x 105 pH 8;Mocheso: 25 °C (1) ACD
Bioconcentration Factor 63600 pH 9;Mocheso: 25 °C (1) ACD
Bioconcentration Factor 11900 pH 10;Mocheso: 25 °C (1) ACD

(1) E baloang ho sebelisoa Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Lik'hemik'hale

Thepa Boleng Boemo Mohloli
Koc 220 pH 1;Mocheso: 25 °C (1) ACD
Koc 4680 pH 2;Mocheso: 25 °C (1) ACD
Koc 42600 pH 3;Mocheso: 25 °C (1) ACD
Koc 1.30 x 105 pH 4;Mocheso: 25 °C (1) ACD
Koc 1.63 x 105 pH 5;Mocheso: 25 °C (1) ACD
Koc 1.67 x 105 pH 6;Mocheso: 25 °C (1) ACD
Koc 1.65 x 105 pH 7;Mocheso: 25 °C (1) ACD
Koc 1.49 x 105 pH 8;Mocheso: 25 °C (1) ACD

 

Thepa Boleng Boemo Mohloli
Koc 76400 pH 9;Mocheso: 25 °C (1) ACD
Koc 14200 pH 10;Mocheso: 25 °C (1) ACD
logD 4.19 pH 1;Mocheso: 25 °C (1) ACD
logD 5.52 pH 2;Mocheso: 25 °C (1) ACD
logD 6.48 pH 3;Mocheso: 25 °C (1) ACD
logD 6.96 pH 4;Mocheso: 25 °C (1) ACD
logD 7.06 pH 5;Mocheso: 25 °C (1) ACD
logD 7.07 pH 6;Mocheso: 25 °C (1) ACD
logD 7.07 pH 7;Mocheso: 25 °C (1) ACD
logD 7.02 pH 8;Mocheso: 25 °C (1) ACD
logD 6.73 pH 9;Mocheso: 25 °C (1) ACD
logD 6.00 pH 10;Mocheso: 25 °C (1) ACD
logP 7.072±0.721 Mocheso: 25 °C (1) ACD
Mass Intrinsic Sollubility 1.2 x 10-4 g/L Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 0.096 g/L pH 1;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 4.3 x 10-3 g/L pH 2;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 4.8 x 10-4 g/L pH 3;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 1.6 x 10-4 g/L pH 4;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 1.2 x 10-4 g/L pH 5;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 1.2 x 10-4 g/L pH 6;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 1.2 x 10-4 g/L pH 7;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 1.4 x 10-4 g/L pH 8;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 2.7 x 10-4 g/L pH 9;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 1.4 x 10-3 g/L pH 10;Mocheso: 25 °C (1) ACD
Ho qhibiliha ka bongata 1.2 x 10-4 g/L Metsi a sa tsitsang pH 7.00;Mocheso: 25 °C (1) ACD
Molar Intrinsic Solubility 1.4 x 10-7 mol/L Mocheso: 25 °C (1) ACD
Molar Solubility 1.1 x 10-4 mol/L pH 1;Mocheso: 25 °C (1) ACD
Molar Solubility 5.0 x 10-6 mol/L pH 2;Mocheso: 25 °C (1) ACD
Molar Solubility 5.5 x 10-7 mol/L pH 3;Mocheso: 25 °C (1) ACD
Molar Solubility 1.8 x 10-7 mol/L pH 4;Mocheso: 25 °C (1) ACD
Molar Solubility 1.4 x 10-7 mol/L pH 5;Mocheso: 25 °C (1) ACD
Molar Solubility 1.4 x 10-7 mol/L pH 6;Mocheso: 25 °C (1) ACD

 

Thepa Boleng Boemo Mohloli
Molar Solubility 1.4 x 10-7 mol/L pH 7;Mocheso: 25 °C (1) ACD
Molar Solubility 1.6 x 10-7 mol/L pH 8;Mocheso: 25 °C (1) ACD
Molar Solubility 3.1 x 10-7 mol/L pH 9;Mocheso: 25 °C (1) ACD
Molar Solubility 1.6 x 10-6 mol/L pH 10;Mocheso: 25 °C (1) ACD
Molar Solubility 1.4 x 10-7 mol/L Metsi a sa tsitsang pH 7.00;Mocheso: 25 °C (1) ACD
Boima ba Molek'hule 869.94    
pKa 9.16±0.20 Mocheso o nang le Asiti ka ho Fetisisa: 25 °C (1) ACD
pKa 3.45±0,70 Mocheso ka ho Fetisisa oa Motheo: 25 °C (1) ACD

(1) E baloang ho sebelisoa Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Lipinski

Thepa Boleng Boemo Mohloli
Li-Bonds tse ka fetolehang ka bolokolohi 19   (1) ACD
H Ba amohelang 16   (1) ACD
H Bafani 2   (1) ACD
H Kakaretso ea Mofani/Moamoheli 18   (1) ACD
logP 7.072±0.721 Mocheso: 25 °C (1) ACD
Boima ba Molek'hule 869.94    

(1) E baloang ho sebelisoa Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Sebopeho se Amanang

Thepa Boleng Mohloli oa Boemo
Sebaka sa Polar Surface 194 A2 (1) ACD

(1) E baloang ho sebelisoa Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Spectra e boletsoeng esale pele

Spectra e fumaneha
1 H NMR
13 C NMR

Lipolelo tsa Kotsi tsa GHS

Khoutu Polelo ea Kotsi Mohloli
H303 E ka ba kotsi haeba e koetsoe Setsebi Curated

  • E fetileng:
  • E 'ngoe:

  • Ngola molaetsa wa hao mona mme o re romele wona