![C50H60N5O10P Sitidin, N-benzoil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' -O- (2-metoksietil)- 5-metil-, 3' - [2-siyanoetil N,N-bis(1-metitil) (1-metitil)I](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C50H60N5O10P Sitidin, N-benzoil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' -O- (2-metoksietil)- 5-metil-, 3' - [2-siyanoetil N,N-bis(1-bis-bis(1-metil)Fetil)](https://www.csnvchem.com/uploads/C50H60N5O10P-Cytidine.png)
C50H60N5O10P Sitidin, N-benzoil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' -O- (2-metoksietil)- 5-metil-, 3' - [2-siyanoetil N,N-bis(1-metitil) (1-metitil)I
CAS ro'yxatga olish raqami
163759-94-2
| Asosiy jismoniy xususiyatlar | Qiymat | Vaziyat |
| Molekulyar og'irlik | 922.01 | - |
| pKa (taxmin qilingan) | 8,59±0,40 | Eng kislotali harorat: 25 °C |
Kanonik tabassum
N#CCCOP(OC1C(OC(N2C=C(C(= NC2=O)NC(=O)C=3C=CC=CC3)C1OCCOC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C 6)N)(CC(C)
Izomerik tabassum
C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@@H](O1)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C(C)=C2)(C4=CC) =C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
InChI
InChI= 1S/C50H60N5O10P/c1-34(2)55(35(3)4)66(63-29-15-28-51)65-44-43(33-62-50(38-18-13-10-14-19-38,349-721-205) )40-22-26-42(60-8)27-23-40)64-48(45(44)61-31-30-58-6)54-32-36(5) )46(53-49(54)57)52-47(56)37-16-11-9-12-17-37/h9-14,16-27,32,34- 35,43-45,48H,15,29-31,33H2,1-8H3,(H,52,53,56,57)/t43-,44-,45-,48-,66?/m1/s1
InChI kaliti
FLIGVMLIIDVDSN-GICDFOIUSA-N
26 Ushbu moddaning boshqa nomlari
sitidin,N-benzoil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' -O-(2-metoksietil)- 5-metil-, 3' - [2-siyanoetil bis(1-metiletil)fosforamidit] (9CI); 12: PN: WO03084478 PAGE: 57 da'vo qilingan DNK; 14: PN: US20030170636 PAGE: 17 da'vo qilingan DNK; 15: PN: U
S20030211606 PAGE: 19 da'vo qilingan DNK; 15: PN: US20030212017 PAGE: 19 da'vo qilingan DNK; 16: PN: US20040005569 PAGE: 22 da'vo qilingan DNK; 17: PN: US20040006030 PAGE: 23 da'vo qilingan DNK; 17: PN: US20040014049 PAGE: 20 da'vo qilingan DNK; 18: PN: US20040014047 PAG E: 20 da'vo qilingan DNK; 18: PN: US20040014048 PAGE: 20 da'vo qilingan DNK; 18: PN: US20040014050 PAGE: 20 da'vo qilingan DNK; 19: PN: U
S20030171313 PAGE: 9 da'vo qilingan DNK; 19: PN: US20030198965 PAGE: 20 da'vo qilingan DNK; 19: PN: US20040005565 PAGE: 17- 22 da'vo qilingan DNK; 19: PN: US20040005570 PAGE: 20 da'vo qilingan DNK; 19: PN: US20040014051 PAGE: 22 da'vo qilingan DNK; 20: PN: US20040014699 PAG
E: 20 da'vo qilingan DNK; 21: PN: US20040006029 PAGE: 23 da'vo qilingan DNK; 21: PN: WO03106645 PAGE: 72 da'vo qilingan DNK; 61: PN: US20030
166592 PAGE: 15 da'vo qilingan DNK; 7: PN: WO2005006958 PAGE: 62 da'vo qilingan DNK; 84: PN: US20040171566 PAGE: 18 da'vo qilingan DNK; 92:
PN: US20040005707 PAGE: 20 da'vo qilingan DNK; 9: PN: WO2005007825 PAGE: 62 da'vo qilingan DNK;N4-benzoil-2' -O-metoksietil-5-O- dimetoksitritil-5-metilsitidin-3' -fosforamidit;N4-benzoil-2' -O-metoksietil-5' -O-dimetoksitritil-5-metilsitidin-3' - amidit
Spektrlar mavjud
13C NMR
Hetero NMR
Xususiyatlari mavjud
Biologik
Kimyoviy
Lipinskiy
Tuzilishi bilan bog'liq
| Mulk | Qiymat | Vaziyat | Manba |
| Biokonsentratsiya omili | 171 | pH 1; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1250 | pH 2; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 47600 | pH 3; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 6,44 x 105 | pH 4; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1,00 x 106 | pH 5; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1,00 x 106 | pH 6; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1,00 x 106 | pH 7; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 7,79 x 105 | pH 8; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 1,63 x 105 | pH 9; Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 30800 | pH 10; Harorat: 25 °C | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
| Mulk | Qiymat | Vaziyat | Manba |
| Koch | 106 | pH 1; Harorat: 25 °C | (1) ACD |
| Koch | 773 | pH 2; Harorat: 25 °C | (1) ACD |
| Koch | 29500 | pH 3; Harorat: 25 °C | (1) ACD |
| Mulk | Qiymat | Vaziyat | Manba |
| Koch | 3,99 x 105 | pH 4; Harorat: 25 °C | (1) ACD |
| Koch | 8,02 x 105 | pH 5; Harorat: 25 °C | (1) ACD |
| Koch | 8,70 x 105 | pH 6; Harorat: 25 °C | (1) ACD |
| Koch | 8,16 x 105 | pH 7; Harorat: 25 °C | (1) ACD |
| Koch | 4,83 x 105 | pH 8; Harorat: 25 °C | (1) ACD |
| Koch | 1,01 x 105 | pH 9; Harorat: 25 °C | (1) ACD |
| Koch | 19100 | pH 10; Harorat: 25 °C | (1) ACD |
| logD | 4.48 | pH 1; Harorat: 25 °C | (1) ACD |
| logD | 5.34 | pH 2; Harorat: 25 °C | (1) ACD |
| logD | 6.92 | pH 3; Harorat: 25 °C | (1) ACD |
| logD | 8.06 | pH 4; Harorat: 25 °C | (1) ACD |
| logD | 8.36 | pH 5; Harorat: 25 °C | (1) ACD |
| logD | 8.39 | pH 6; Harorat: 25 °C | (1) ACD |
| logD | 8.37 | pH 7; Harorat: 25 °C | (1) ACD |
| logD | 8.14 | pH 8; Harorat: 25 °C | (1) ACD |
| logD | 7.46 | pH 9; Harorat: 25 °C | (1) ACD |
| logD | 6.73 | pH 10; Harorat: 25 °C | (1) ACD |
| logP | 8,401±0,723 | Harorat: 25 °C | (1) ACD |
| Massaning ichki eruvchanligi | 1,4 x 10-4 g/l | Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,1 g/l | pH 1; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 0,16 g/l | pH 2; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 4,1 x 10-3 g/L | pH 3; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 3,0 x 10-4 g/L | pH 4; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,5 x 10-4 g/l | pH 5; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,4 x 10-4 g/l | pH 6; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,5 x 10-4 g/l | pH 7; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 2,5 x 10-4 g/l | pH 8; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,2 x 10-3 g/L | pH 9; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 6,3 x 10-3 g/l | pH 10; Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,5 x 10-4 g/l | Bufersiz suv pH 6,97; Harorat: 25 °C | (1) ACD |
| Molar ichki eruvchanligi | 1,5 x 10-7 mol/l | Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,2 x 10-3 mol/L | pH 1; Harorat: 25 °C | (1) ACD |
| Mulk | Qiymat | Vaziyat | Manba |
| Molyar eruvchanlik | 1,7 x 10-4 mol/l | pH 2; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 4,4 x 10-6 mol/L | pH 3; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 3,2 x 10-7 mol/L | pH 4; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,6 x 10-7 mol/l | pH 5; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,5 x 10-7 mol/l | pH 6; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,6 x 10-7 mol/l | pH 7; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 2,7 x 10-7 mol/L | pH 8; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,3 x 10-6 mol/L | pH 9; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 6,8 x 10-6 mol/L | pH 10; Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,6 x 10-7 mol/l | Bufersiz suv pH 6,97; Harorat: 25 °C | (1) ACD |
| Molekulyar og'irlik | 922.01 | ||
| pKa | 8,59±0,40 | Eng kislotali harorat: 25 °C | (1) ACD |
| pKa | 3,87±0,20 | Eng asosiy harorat: 25 °C | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
| Mulk | Qiymat | Vaziyat | Manba |
| Erkin aylanadigan obligatsiyalar | 22 | (1) ACD | |
| H qabul qiluvchilar | 15 | (1) ACD | |
| H Donorlar | 1 | (1) ACD | |
| H Donor/akseptor summasi | 16 | (1) ACD | |
| logP | 8,401±0,723 | Harorat: 25 °C | (1) ACD |
| Molekulyar og'irlik | 922.01 |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
| Mulk | Qiymat | Vaziyat manbai |
| Qutb yuzasi maydoni | 176 A2 | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
Spektrlar mavjud
1H NMR
13C NMR
![C42H52N5O9P Sitidin, N-asetil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' -O- metil-, 3' - [2-siyanoetil N,N-bis(1-metiletil)fosforamidit] (ACI)](https://www.csnvchem.com/uploads/C42H52N5O9P-Cytidine-300x300.png)
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