![C42H52N5O9P Sitidin, N-asetil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' -O- metil-, 3' - [2-siyanoetil N,N-bis(1-metiletil)fosforamidit] ( ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C42H52N5O9P Sitidin, N-asetil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' -O- metil-, 3' - [2-siyanoetil N,N-bis(1-metiletil)fosforamidit] ( ACI) Tavsiya etilgan rasm](https://www.csnvchem.com/uploads/C42H52N5O9P-Cytidine.png)
C42H52N5O9P Sitidin, N-asetil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' -O- metil-, 3' - [2-siyanoetil N,N-bis(1-metiletil)fosforamidit] ( ACI)
CAS ro'yxatga olish raqami
199593-09-4
| Asosiy jismoniy xususiyatlar | Qiymat | Vaziyat |
| Molekulyar og'irlik | 801.87 | - |
| pKa (taxmin qilingan) | 10,18±0,20 | Eng kislotali harorat: 25 °C |
Kanonik tabassum
N#CCCOP(OC1C(OC(N2C=CC(= NC2=O)NC(=O)C)C1OC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5 =CC=C(OC)C=C5)N(C(C)C)C(C)C
Izomerik tabassum
C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@@ H](O1)N2C(=O)N=C(NC(C)=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC =C(OC)C=C4 )C5=CC=CC=C5
InChI
InChI= 1S/C42H52N5O9P/c1-28(2)47(29(3)4)57(54-26-12-24-43)56-38-36(55-40(39(38)52-8) 46-25-23-37(44-30(5)48)45-41(46)49)27-53 -42(31-13-10-9-11-14-31,32-15-19- 34(50-6)20-16-32)33-17-21-35(51-7)22-18-33/h9-11,13-23,25,28-29,36,38-40H, 12,26-27H2,1-8H3,( H,44,45,48,49)/t36-,38-,39-,40-,57?/m1/s1
InChI kaliti
WNWUMIPFLOKTEZ-UAQIPLLRSA-N
1 Ushbu moddaning boshqa nomi
sitidin,N-asetil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' -O-metil-, 3' - [2-siyanoetil bis(1-metiletil)fosforamidit] (9CI)
Xususiyatlari mavjud
Biologik
Kimyoviy
Lipinskiy
Tuzilishi bilan bog'liq
| Mulk | Qiymat | Vaziyat | Manba |
| Biokonsentratsiya omili | 4.77 | pH 1;Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 50.1 | pH 2;Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 2190 | pH 3;Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 21700 | pH 4;Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 35700 | pH 5;Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 37800 | pH 6;Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 37900 | pH 7;Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 37300 | pH 8;Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 31400 | pH 9;Harorat: 25 °C | (1) ACD |
| Biokonsentratsiya omili | 12300 | pH 10;Harorat: 25 °C | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
| Mulk qiymati Vaziyat Manba |
| Koc 8,29 pH 1;Harorat: 25 °C (1) ACD |
| Koc 87,1 pH 2;Harorat: 25 °C (1) ACD |
| Koc 3800 pH 3;Harorat: 25 °C (1) ACD |
| Koc 37700 pH 4;Harorat: 25 °C (1) ACD |
| Koc 62000 pH 5;Harorat: 25 °C (1) ACD |
| Koc 65700 pH 6;Harorat: 25 °C (1) ACD |
| Koc 65900 pH 7;Harorat: 25 °C (1) ACD |
| Koc 64700 pH 8;Harorat: 25 °C (1) ACD |
| Koc 54500 pH 9;Harorat: 25 °C (1) ACD |
| Koc 21400 pH 10;Harorat: 25 °C (1) ACD |
| logD 2,43 pH 1;Harorat: 25 °C (1) ACD |
| logD 3,45 pH 2;Harorat: 25 °C (1) ACD |
| logD 5,09 pH 3;Harorat: 25 °C (1) ACD |
| Mulk | Qiymat | Vaziyat | Manba |
| logD | 6.09 | pH 4;Harorat: 25 °C | (1) ACD |
| logD | 6.30 | pH 5;Harorat: 25 °C | (1) ACD |
| logD | 6.33 | pH 6;Harorat: 25 °C | (1) ACD |
| logD | 6.33 | pH 7;Harorat: 25 °C | (1) ACD |
| logD | 6.32 | pH 8;Harorat: 25 °C | (1) ACD |
| logD | 6.25 | pH 9;Harorat: 25 °C | (1) ACD |
| logD | 5.84 | pH 10;Harorat: 25 °C | (1) ACD |
| logP | 6,329±0,771 | Harorat: 25 °C | (1) ACD |
| Massaning ichki eruvchanligi | 1,8 x 10-4 g/L | Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,4 g/l | pH 1;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 0,14 g/l | pH 2;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 3,1 x 10-3 g/L | pH 3;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 3,2 x 10-4 g/l | pH 4;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,9 x 10-4 g/l | pH 5;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,8 x 10-4 g/L | pH 6;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,8 x 10-4 g/L | pH 7;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,8 x 10-4 g/L | pH 8;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 2,2 x 10-4 g/l | pH 9;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 5,6 x 10-4 g/l | pH 10;Harorat: 25 °C | (1) ACD |
| Ommaviy eruvchanlik | 1,8 x 10-4 g/L | Bufersiz suv pH 7.00;Harorat: 25 °C | (1) ACD |
| Molar ichki eruvchanligi | 2,3 x 10-7 mol/L | Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,8 x 10-3 mol/L | pH 1;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 1,7 x 10-4 mol/L | pH 2;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 3,9 x 10-6 mol/L | pH 3;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 4,0 x 10-7 mol/L | pH 4;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 2,4 x 10-7 mol/L | pH 5;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 2,3 x 10-7 mol/L | pH 6;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 2,3 x 10-7 mol/L | pH 7;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 2,3 x 10-7 mol/L | pH 8;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 2,8 x 10-7 mol/L | pH 9;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 7,0 x 10-7 mol/L | pH 10;Harorat: 25 °C | (1) ACD |
| Molyar eruvchanlik | 2,3 x 10-7 mol/L | Bufersiz suv pH 7.00;Harorat: 25 °C | (1) ACD |
| Mulk | Qiymat | Vaziyat | Manba |
| Molekulyar og'irlik | 801.87 | ||
| pKa | 10,18±0,20 | Eng kislotali harorat: 25 °C | (1) ACD |
| pKa | 3,57±0,20 | Eng asosiy harorat: 25 °C | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
| Mulk | Qiymat | Vaziyat | Manba |
| Erkin aylanadigan obligatsiyalar | 18 | (1) ACD | |
| H qabul qiluvchilar | 14 | (1) ACD | |
| H Donorlar | 1 | (1) ACD | |
| H Donor/akseptor summasi | 15 | (1) ACD | |
| logP | 6,329±0,771 | Harorat: 25 °C | (1) ACD |
| Molekulyar og'irlik | 801.87 |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
| Mulk | Qiymat | Vaziyat manbai |
| Qutb yuzasi maydoni | 167 A2 | (1) ACD |
(1) Ilg'or kimyoni ishlab chiqish (ACD/Labs) V11.02 dasturiy ta'minoti yordamida hisoblangan (© 1994-2023 ACD/Labs)
Spektrlar mavjud
1H NMR
13C NMR
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![C41H49FN5O8P Sitidin, N-asetil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' - deoksi-2' -ftor-, 3' - [2-siyanoetil N,N-bis(1-metiletil) fosfor amidit] (ACI)](https://www.csnvchem.com/uploads/C41H49FN5O8P-Cytidine-300x300.png)
![C48H54N7O8P Adenozin, N-benzoil-5' -O- [bis(4-metoksifenil)fenilmetil]-2' - O-metil-, 3' - [2-siyanoetil N,N-bis(1-metiletil)fosfor amidit] (ACI)](https://www.csnvchem.com/uploads/C48H54N7O8P-300x300.png)