2-hydroxypyridine-N-oxide (HOPO)
Basic Information:
Chemical name: 2-hydroxypyridine-n-oxide;
CAS number: 13161-30-3
Molecular formula: C5H5NO2
Molecular weight: 111.1
EINECS number: 236-100-88
Structural formula：
Related categories: Pharmaceutical intermediates; Polypeptide reagent – shrinkage mixture; Organic chemical raw materials.
Melting point: 147-152 °C
Boiling point: 387.7±15.0 °C(Predicted)
Density: 1.111 Flash point: 100 °C
Refractive index: 1.554
Vapor pressure: 0.223Pa at 25 °C
Solubility: slightly soluble in chloroform, DMSO, methanol, water.
Properties: Yellow to light yellow powder.
LogP: -1.07at 25℃
| Specification | Unit | Standard |
| Appearance | Yellow to light yellow powder | |
| Loss on drying | % | ≤0.5 |
| Melting point | ℃ | 149-152 |
It can be used as shrinkage agent, catalyst and auxiliary agent. In peptide synthesis, the addition of condensation auxiliaries can speed up the reaction speed and reduce racemization, so as to make up for the shortage of condensation reagents. HOPO is a variety of such condensation auxiliaries. 2-hydroxypyridine-n-oxide is an important compound. Recent studies have found that this compound has a special role in preventing wood degradation due to white-rotfungi. At the same time, it is a new and effective subway chelating agent. The complex formed by the compound and vanadium also plays an important role in biochemistry.
25kg/ bag, or other packing methods according to customer requirements;
This product should be stored in a dry, cool and ventilated place.
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