![C43H55N4O10P Uridin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C43H55N4O10P Uridin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI) Ausgewielt Bild](https://www.csnvchem.com/uploads/C43H55N4O10P-Uridine.png)
C43H55N4O10P Uridin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)
CAS-Registrierungsnummer
163878-63-5
H302
| Schlësselphysikalesch Eegeschaften | Wäert | Zoustand |
| Molekulargewiicht | 818,89 | - |
| pKa (Virausbezunnen) | 9,55±0,10 | Säurege Temperatur: 25 °C |
Kanonesch Laachen
N#CCCOP(OC1C(OC(N2C=C(C(=O)NC2=O)C)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
Isomeresch Laachen
C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@@H](O1)N2C(=O)NC(=O)C(C)=C2)(C3=CC=C(OC)C=C3)(C4=CC =C(OC)C=C4)C5=CC=CC=C5
InChI
InChI= 1S/C43H55N4O10P/c1-29(2)47(30(3)4)58(55-24-12-23-44)57-38-37(56-41(39(38)53-26-25-50-6)46-27-50-425(425)46-27-425(425) 8-54-43(32-13-10-9-11-14-32,33-15-19-35(51-7)20-16-33)34-17-21-36(52-8)22-18-34/h9-11,13-22,27,29-30,37-39,41H,12,24-26,28H2, 1-8H3,(H,45,48,49)/t37-,38-,39-,41-,58?/m1/s1
InChI Schlëssel
YFRRKZDUDXHJNC-KZQAAKLLSA-N
17 aner Nimm fir dës Substanz
Uridin, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-Methoxyethyl)-5-methyl-, 3'-[2-cyanoethylbis(1-methylethyl)phosphor
Amidit] (9CI); 10: PN: US20030212017 Säit: 18 behaapt RNA; 11: PN: US20030211606 Säit: 18 behaapt RNA; 13: PN: US20040
005569 Säit: 21 behaapt RNA; 13: PN: US20040006030 Säit: 22 behaapt RNA; 13: PN: US20040014048 Säit: 19 behaapt RNA; 13: PN: US20040014049 Säit: 19 behaapt RNA; 14: PN: US20030198965 Säit: 19 behaapt RNA; 14: PN: US20040005565 Säit: 17- 22 behaapt RNA; 14: PN: US20040005570 Säit: 19 behaapt RNA; 14: PN: US20040014047 Säit: 19 behaapt RNA; 14: PN: US20040
014699 Säit: 19 behaapt RNA; 15: PN: US20040014050 Säit: 19 behaapt RNA; 15: PN: US20040014051 Säit: 21 behaapt RNA; 15:
PN: WO03106645 Säit: 69 behaapt RNA; 16: PN: US20040006029 Säit: 22 behaapt RNA; 87: PN: US20040005707 Säit: 19 behaapt RNA
Spektren verfügbar
1H NMR
13C NMR
Hetero-NMR
Verfügbar Immobilien
Biologesch
Chemesch
Lipinski
Strukturbezunnen
| Immobilie | Wäert | Zoustand | Quell |
| Biokonzentratiounsfaktor | 348 | pH 1; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 2810 | pH 2; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 21100 | pH 3; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 63100 | pH 4; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 78800 | pH 5; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 80800 | pH 6; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 80800 | pH 7; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 78800 | pH 8; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 63400 | pH 9; Temperatur: 25 °C | (1) ACD |
| Biokonzentratiounsfaktor | 21800 | pH 10; Temperatur: 25 °C | (1) ACD |
(1) Berechent mat der Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Immobilie | Wäert | Zoustand | Quell |
| Koc | 487 | pH 1; Temperatur: 25 °C | (1) ACD |
| Koc | 3940 | pH 2; Temperatur: 25 °C | (1) ACD |
| Koc | 29600 | pH 3; Temperatur: 25 °C | (1) ACD |
| Koc | 88400 | pH 4; Temperatur: 25 °C | (1) ACD |
| Immobilie | Wäert | Zoustand | Quell |
| Koc | 1,10 x 105 | pH 5; Temperatur: 25 °C | (1) ACD |
| Koc | 1,13 x 105 | pH 6; Temperatur: 25 °C | (1) ACD |
| Koc | 1,13 x 105 | pH 7; Temperatur: 25 °C | (1) ACD |
| Koc | 1,10 x 105 | pH 8; Temperatur: 25 °C | (1) ACD |
| Koc | 88800 | pH 9; Temperatur: 25 °C | (1) ACD |
| Koc | 30600 | pH 10; Temperatur: 25 °C | (1) ACD |
| logD | 4,39 | pH 1; Temperatur: 25 °C | (1) ACD |
| logD | 5.30 Auer | pH 2; Temperatur: 25 °C | (1) ACD |
| logD | 6.18 | pH 3; Temperatur: 25 °C | (1) ACD |
| logD | 6,65 | pH 4; Temperatur: 25 °C | (1) ACD |
| logD | 6,75 | pH 5; Temperatur: 25 °C | (1) ACD |
| logD | 6,76 | pH 6; Temperatur: 25 °C | (1) ACD |
| logD | 6,76 | pH 7; Temperatur: 25 °C | (1) ACD |
| logD | 6,75 | pH 8; Temperatur: 25 °C | (1) ACD |
| logD | 6,65 | pH 9; Temperatur: 25 °C | (1) ACD |
| logD | 6.19 | pH 10; Temperatur: 25 °C | (1) ACD |
| logP | 6,761±0,669 | Temperatur: 25 °C | (1) ACD |
| Masse intrinsesch Léislechkeet | 2,0 x 10⁻⁴ g/L | Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 0,046 g/L | pH 1; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 5,7 x 10-3 g/L | pH 2; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 7,6 x 10⁻⁴ g/L | pH 3; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,5 x 10-4 g/L | pH 4; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,0 x 10⁻⁴ g/L | pH 5; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,0 x 10⁻⁴ g/L | pH 6; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,0 x 10⁻⁴ g/L | pH 7; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,0 x 10⁻⁴ g/L | pH 8; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,5 x 10-4 g/L | pH 9; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 7,4 x 10-4 g/L | pH 10; Temperatur: 25 °C | (1) ACD |
| Masselöslechkeet | 2,0 x 10⁻⁴ g/L | Ongepuffert Waasser pH 7,00; Temperatur: 25 °C | (1) ACD |
| Molar intrinsesch Léislechkeet | 2,4 x 10⁻⁶ mol/L | Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 5,6 x 10⁻⁶ mol/L | pH 1; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 7,0 x 10⁻⁶ mol/L | pH 2; Temperatur: 25 °C | (1) ACD |
| Immobilie | Wäert | Zoustand | Quell |
| Molar Löslechkeet | 9,3 x 10⁻⁶ mol/L | pH 3; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 3,1 x 10⁻⁶ mol/L | pH 4; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 2,5 x 10⁻⁶ mol/L | pH 5; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 2,4 x 10⁻⁶ mol/L | pH 6; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 2,4 x 10⁻⁶ mol/L | pH 7; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 2,5 x 10⁻⁶ mol/L | pH 8; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 3,1 x 10⁻⁶ mol/L | pH 9; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 9,0 x 10⁻⁶ mol/L | pH 10; Temperatur: 25 °C | (1) ACD |
| Molar Löslechkeet | 2,4 x 10⁻⁶ mol/L | Ongepuffert Waasser pH 7,00; Temperatur: 25 °C | (1) ACD |
| Molekulargewiicht | 818,89 | ||
| pKa | 9,55±0,10 | Säurege Temperatur: 25 °C | (1) ACD |
| pKa | 3,45±0,70 | Basis Temperatur: 25 °C | (1) ACD |
(1) Berechent mat der Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Immobilie | Wäert | Zoustand | Quell |
| Fräi rotéierbar Bindungen | 21 | (1) ACD | |
| H-Akzeptoren | 14 | (1) ACD | |
| H Spender | 1 | (1) ACD | |
| H Donateur/Akzeptant Zomm | 15 | (1) ACD | |
| logP | 6,761±0,669 | Temperatur: 25 °C | (1) ACD |
| Molekulargewiicht | 818,89 |
(1) Berechent mat der Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Immobilie | Wäert | Quell vun der Konditioun |
| Polarfläche | 164 A2 | (1) ACD |
(1) Berechent mat der Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Spektren verfügbar
1H NMR
13C NMR
| Quell vun der Geforenausso vum Code | |
| H302 Schiedlech beim Verschlécken | Klassifikatioun a Kennzeechnung vun der Europäescher Chemikalienagentur (ECHA) Inventar - Notifizéiert Klassifikatioun an Etikettéierung - déi heefegst Notifikatiounen, Europäesch Chemikalienagentur (ECHA) Inventar vun der Klassifikatioun a vum Etikettéierungsregister - Notifizéiert Klassifikatioun a Etikettéierung - déi eeschtst Notifikatiounen |
![C53H66N7O8PSi CAS-Nr.: 104992-55-4 Adenosin, N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′–O-[(1,1-dimethylethyl)dimethylsilyl]-, 3′–[2-cyanoethyl N,N-bis(1-methylethyl)...](https://www.csnvchem.com/uploads/C53H66N7O8PSi-300x300.png)
![C47H51FN7O7P Adenosin, N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluor-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C47H51FN7O7P-Adenosine-300x300.png)
![C48H54N7O8P Adenosin, N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′–O-methyl-, 3′–[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C48H54N7O8P-300x300.png)
![C41H49FN5O8P Cytidin, N-Acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluor-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C41H49FN5O8P-Cytidine-300x300.png)
![C40H49N4O9P Uridin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C40H49N4O9P-Uridine-300x300.png)
![C42H52N5O9P Cytidin, N-Acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] (ACI)](https://www.csnvchem.com/uploads/C42H52N5O9P-Cytidine-300x300.png)