5-Bromo-2-chloropyrimidine 98% min

product

5-Bromo-2-chloropyrimidine 98% min

Basic Information:

Product Name:5-Bromo-2-chloropyrimidine

Synonyms: PYRIMIDINE,5-BROMO-2-CHLORO-;2-chloro-5-broMopyriMidine(5-broMo-2-chloropyriMidine);2-chloro-5-broMo-uracil;5-broMine-2-chloropyriChemicalbookMidine;5-methyl-4,5-dihydrothiazol-2-amine;MacitentanIntermediate5;MacitentanImpurity27;5-BROMO-2-CHLOROPYRIMIDINE

CAS NO.: 32779-36-5

Molecular formula: C4H2BrClN2

Molecular weight: 193.43

EINECS NO: 629-214-8

Structural formula

5-Bromo-2-chloropyrimidine


Product Detail

Product Tags

Physical and Chemical properties

Appearance and characteristics

Shape: solid

Odor: no data

Odor threshold: no data

PH value: no data

Melting point/freezing point: 73-79 ℃ -lit.

Boiling point, initial boiling point and boiling range: no data

Flash point: no data

Evaporation rate: no data

Flammability (solid, gas): no data

High/low flammability or explosive limit: no data

Vapor pressure: No data

Vapor density: no data

Density/relative density: no data

Water solubility: no data

N-octano l/water distribution coefficient: no data

Spontaneous combustion temperature: no data

Decomposition temperature: no data

Viscosity: No data

Storage conditions : Keep the storage device sealed and stored in a cool, dry place. Ensure that the work room is well ventilated

Solubility: soluble in Methanol

Water soluble: insoluble

Incompatible substances: strong oxidizing agent

Chemical Reaction

5-bromo-2-chloropyrimidine is somewhat alkaline, insoluble in water but soluble in common organic solvents, including methylene chloride and chloroform. Due to the lack of electron properties of pyrimidine, the chlorine atoms in its structure can undergo the dechlorination functional group reaction under the attack of nucleophiles, common nucleophiles include alcohols, amines and chemicalbooks. In the presence of a nucleophile, oxygen or nitrogen atoms in the nucleophile attack the chlorine atoms in 5-bromo-2-chloropyrimidine, forming intermediates that are accompanied by cleavage and recombination reactions. In addition, the bromine atoms on the pyrimidine ring can undergo various coupling reactions with the standard reagent and organic zinc reagent under the action of transition metals.

Storage Condition

Keep the storage device sealed and stored in a cool, dry place. Ensure that the work room is well ventilated

Package

Packed in 25kg/drum , lined with double plastic bags, or according to customer requirements.

Application Fields

It is a heterocyclic derivative, mainly used as a pharmaceutical intermediate.

Storage Condition

Keep the storage device sealed and stored in a cool, dry place. Ensure that the work room is well ventilated

Package

Packed in 25kg/drum , lined with double plastic bags, or according to customer requirements.

Application Fields

It is a heterocyclic derivative, mainly used as a pharmaceutical intermediate.


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